Guide to 4-Chlorophenylboronic Acid CAS 1679-18-1: Properties, Uses, and Sourcing

4-Chlorophenylboronic acid, also called 4-chlorobenzeneboronic acid, is an organoboron compound used primarily as an aryl coupling partner in carbon–carbon bond-forming chemistry. Its CAS Registry Number is 1679-18-1, its molecular formula is C₆H₆BClO₂, and its molecular weight is 156.37 g/mol. Buyers typically evaluate it by identity, assay, impurity profile, packaging, and fitness for the intended reaction—not by the chemical name alone. This guide explains the compound’s properties and uses, and provides a practical framework for assessing suppliers and requesting a quotation.

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Key Takeaways

• 4-Chlorophenylboronic acid is an arylboronic acid used in synthesis, especially as a coupling partner in Suzuki–Miyaura reactions.
• Confirm the CAS number, formula, assay method, and impurity requirements against your process before ordering.
• Purity, packaging, minimum order quantity, and lead time should be confirmed for the specific grade and batch offered.
• Maison Chemical can discuss product requirements and supply options with B2B buyers; availability and commercial terms should be confirmed by inquiry.

Who This Guide Is For

This guide is intended for procurement teams, process chemists, research organizations, and manufacturers assessing 4-Chlorophenylboronic acid as a raw material or intermediate. It is useful when comparing product specifications, reviewing a new supplier, or planning a sourcing request for laboratory, development, or production use. The information is general and does not replace batch-specific documentation or a review by your technical and quality teams. Buyers should ensure the material and its documentation meet their own regulatory, safety, and process requirements.

Basic Properties and Chemical Context

Identity and Structure

The molecule contains a phenyl ring bearing chlorine at the para, or 4-position, and a boronic acid group attached to the ring. This combination gives the compound two useful structural features: an aryl group that can be transferred in coupling chemistry and a chlorine substituent that may be retained or further modified, depending on the reaction route. When preparing an inquiry, use both the full chemical name and CAS 1679-18-1 to reduce the risk of confusion with positional isomers or related boronic acids. The CAS number is an identifier, not a substitute for checking the supplier’s product specification.

Physical and Handling Considerations

Commercial descriptions commonly identify the material as a solid, but color, particle form, and other appearance details should be confirmed against the current product specification. A melting range around 284–288 °C is reported for this compound; published or catalog values may differ in method and may involve decomposition, so it should not be treated as a batch acceptance criterion without agreement. Ask for the supplier’s stated test method and batch-specific result if melting behavior is relevant to your application. For storage, handling, and protective equipment, follow the supplier’s Safety Data Sheet and your site procedures rather than relying on a generic description.

Uses and Application Matching

Synthetic Chemistry

The principal use of 4-Chlorophenylboronic acid is as a reagent in Suzuki–Miyaura cross-coupling, where an aryl group can be coupled with a suitable organic halide or related electrophile under appropriate catalytic conditions. The reaction outcome depends on the substrate, catalyst system, base, solvent, water content, and operating conditions; the presence of a boronic acid alone does not guarantee a particular yield or selectivity. The para-chloro substituent can provide a functional handle for a planned synthesis, but whether it remains intact depends on reaction design. Process chemists should evaluate the complete route and confirm compatibility through appropriate development work.

The compound may be considered in the preparation of fine chemicals, research intermediates, and other molecules that incorporate a 4-chlorophenyl group. Its suitability depends on the target structure and the required downstream transformations. For regulated or commercial manufacturing, buyers should also review impurity control, traceability, change notification expectations, and documentation with their internal quality teams. A supplier’s general product listing is not, by itself, evidence that a material meets a buyer’s specific process or regulatory requirements.

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How to Select a Grade and Specification

Set Requirements Around the Intended Use

Begin by defining the role of the material: exploratory research, route development, scale-up, or routine manufacturing. These uses may call for different levels of documentation, packaging, and impurity control. Establish which attributes are critical to your process before comparing quotations, and distinguish mandatory acceptance limits from preferences. If you are setting an initial assay requirement, a threshold such as ≥97% may be used as a buyer-defined example, but it is not a claim about Maison Chemical’s current grade; confirm the offered value and test method in writing.

Review the Batch Documentation

Request a current specification and, where available, a batch-specific Certificate of Analysis for the material being offered. Check the stated assay, identification tests, relevant impurities, analytical methods, and retest or validity information, as applicable. Confirm that the product name, CAS number, batch number, and packaging description are consistent across the quotation and documentation. If a particular impurity could affect your reaction or downstream product, discuss a justified limit with the supplier before placing an order.

Pricing, MOQ, and Lead Time

Pricing for a specialty chemical can depend on requested quantity, grade, packaging, documentation, production or stock status, and delivery destination. Minimum order quantity and lead time are therefore quotation-specific rather than fixed assumptions. For a usable comparison, ask each supplier to quote the same quantity, specification, packaging basis, and delivery terms. Also confirm whether the quoted lead time begins after order confirmation, payment, or another agreed milestone.

For planning, share your expected quantity and required delivery window early, while making clear which details are flexible. If you need repeated supply, ask about the process for confirming future availability and whether the product specification can be maintained across orders. Do not assume that a quoted price, stock position, or delivery estimate applies to later batches. Maison Chemical can review your inquiry and confirm the available commercial terms for the requested specification.

Supplier Evaluation Checklist

• Identity: Does the quotation specify 4-Chlorophenylboronic acid and CAS 1679-18-1?
• Specification: Are assay, test methods, and relevant impurity requirements clear?
• Documentation: Can the supplier provide the documents your organization requires for evaluation and receipt?
• Packaging: Is the proposed pack size suitable for transport, storage, and use at your site?
• Commercial terms: Are MOQ, price basis, lead time, payment terms, and delivery responsibilities stated?
• Communication: Can the supplier respond clearly to technical and purchasing questions before order placement?

For a first purchase, align the specification and acceptance criteria before shipment rather than relying on a product name or a general purity description. If a sample or preliminary evaluation is part of your qualification process, confirm its availability, terms, and relationship to the commercial batch. Keep the agreed specification and documentation requirements in the purchase record. These steps help reduce avoidable mismatches between the material quoted and the material your process requires.

Conclusion and Next Steps

4-Chlorophenylboronic acid CAS 1679-18-1 is an arylboronic acid used chiefly as a coupling partner in synthesis, with a molecular weight of 156.37 g/mol and a structure that includes a para-chloro substituent. The right sourcing decision depends on more than identity: buyers should match grade, assay, impurity controls, documentation, packaging, MOQ, and lead time to the intended application. Reported physical values can help with preliminary checks, but batch-specific supplier documents should guide purchasing and acceptance decisions. To evaluate supply from Maison Chemical, send your required quantity, target specification, documentation needs, destination, and requested delivery window for a tailored B2B inquiry.

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